Stylish hotel in downtown Winston-Salem offering easy access to interstate, university and more.

We have reserved a hotel room block here for our guests.

Step through Graylyn’s 15th-century French-carved doorway and discover a manor that is nothing short of a masterpiece – an enchanting piece of history that honors the life and legacy of the Gray family. But beyond its grand archways and gilded finishes, this storied estate holds a special secret.

A warm and welcoming boutique hotel where charming butlers treat arriving guests like royalty.

Welcome to Kimpton Cardinal Hotel, where a rich Southern legacy is tempered with a smidge of spunk. We are located in downtown Winston-Salem’s historic R.J. Reynolds building, the architectural muse for the Empire State Building.

Located in the center of downtown Winston-Salem in the historic Pepper Building, the pet friendly Hotel Indigo Winston-Salem Downtown effortlessly blends into the Art Deco-inspired architecture of the neighborhood.